Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL851377 | 0.91 | MEN1 (0.68) | FFAR1FFAR4MEN1KMT2AALKBH1 | |
| SCHEMBL851678 | 0.89 | MEN1 (0.60) | FFAR1FFAR4MEN1KMT2AALKBH1 | |
| SCHEMBL851521 | 0.86 | MAOB (0.58) | FFAR1MEN1KMT2AMRGPRX4MAOB | |
| SCHEMBL851554 | 0.85 | FFAR1 (0.53) | FFAR1FFAR4ALKBH1MRGPRX4MAOB | |
| SCHEMBL4684138 | 0.83 | MRGPRX4 (0.70) | MRGPRX4NR4A2 | |
| SCHEMBL25203039 | 0.82 | NR4A2 (0.71) | FFAR1FFAR4ALKBH1MRGPRX4NR4A2 | |
| SCHEMBL30391969 | 0.82 | NR4A2 (0.71) | FFAR1FFAR4ALKBH1MRGPRX4NR4A2 | |
| SCHEMBL851769 | 0.82 | MEN1 (0.51) | FFAR1FFAR4MEN1KMT2AMAOB | |
| SCHEMBL852236 | 0.82 | MEN1 (0.69) | MEN1KMT2AALKBH1MRGPRX4MAOB | |
| SCHEMBL851979 | 0.82 | PARP15 (0.62) | MEN1KMT2ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140200225-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2014-07-17 | — | — | US | disclosed |
| US-8722930-B2 | Protease inhibitors | ORION CORPORATION (FI) | 2014-05-13 | — | — | US | disclosed |
| US-20120136002-A1 | PROTEASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2012-05-31 | — | — | US | disclosed |
| EP-2432556-A1 | PROTEASE INHIBITORS | Orion Corporation (FI) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133748-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200225-A1 | PROTEASE INHIBITORS | SERPINB1, TMPRSS15, PRSS1 | FFAR1 3640/4885FFAR4 4056/4885MEN1 258/4885 |
| US-20120136002-A1 | PROTEASE INHIBITORS | SERPINB1, TMPRSS15, PRSS1 | FFAR1 3640/4885FFAR4 4056/4885MEN1 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.