Phosphoric Acid

Phosphoric Acid

SCHEMBL8514542

CC(=O)NCCCC(=O)O.O=P(O)(O)O

nearest known ligand 0.70

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ADRA1A known ✓ P35348 1/20 0.70
MAPK1 P28482 2/20 0.54
KDM4E B2RXH2 1/20 0.54
HIF1A Q16665 1/20 0.54
PRMT1 Q99873 1/20 0.47
FOLH1 Q04609 1/20 0.46
PAOX Q6QHF9 3/20 0.45
PLA2G4A P47712 1/20 0.44
LMNA P02545 1/20 0.43
FABP4 P15090 1/20 0.43
ATM Q13315 1/20 0.41
PLA2G2A P14555 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
SLC22A6 Q4U2R8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL285421 0.91 ADRA1A (0.83) ADRA1AMAPK1KDM4EHIF1APRMT1
Hydrochloric Acid SCHEMBL11026786 0.89 ADRA1A (0.79) ADRA1AMAPK1KDM4EHIF1APRMT1
SCHEMBL1331412 0.85 ADRA1A (0.95) ADRA1AMAPK1KDM4EHIF1APRMT1
SCHEMBL18878631 0.83 ADRA1A (0.70) ADRA1AMAPK1KDM4EHIF1APRMT1
SCHEMBL29061522 0.83 ADRA1A (0.70) ADRA1AMAPK1KDM4EHIF1APRMT1
SCHEMBL8098661 0.83 ADRA1A (1.00) ADRA1AMAPK1KDM4EHIF1APRMT1
Acexamic Acid SCHEMBL24435 0.83 ADRA1A (1.00) ADRA1AMAPK1KDM4EHIF1APRMT1
SCHEMBL11399083 0.83 ADRA1A (1.00) ADRA1AMAPK1KDM4EHIF1APRMT1
SCHEMBL1001209 0.83 ADRA1A (1.00) ADRA1AMAPK1KDM4EHIF1APRMT1
SCHEMBL22199749 0.83 ADRA1A (1.00) ADRA1AMAPK1KDM4EHIF1APRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2456879-B1 PROCESS FOR PREPARING 1,4-BUTANEDIAMINE VIA N-PROTECTED 1,4-BUTANEDIAMINE DSM IP ASSETS BV (NL) 2018-04-04 EP disclosed
CN-105132486-A PROCESS FOR THE PREPARATION OF 1,4-BUTANEDIAMINE VIA N-ACYL OR N-GUANIDYL PROTECTED 1,4-BUTANEDIAMINE PRECURSORS DSM IP ASSETS BV 2015-12-09 CN disclosed
CN-102471789-B Process for the preparation of 1, 4-butanediamine via N-acyl or N-guanidino protected 1, 4-butanediamine precursors DSM IP ASSETS B.V. (NL) 2015-08-19 CN disclosed
US-8999680-B2 Preparation of 1,4-diaminobutane DSM IP ASSETS B.V. (NL) 2015-04-07 US disclosed
US-20120190087-A1 PREPARATION OF 1,4-DIAMINOBUTANE ENVALIOR B.V. (NL) 2012-07-26 US disclosed
EP-2456879-A1 PROCESS FOR THE PREPARATION OF 1,4-BUTANEDIAMINE VIA N-ACYL OR N-GUANIDYL PROTECTED 1,4-BUTANEDIAMINE PRECURSORS DSM IP Assets B.V. (NL) 2012-05-30 EP disclosed