Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 5/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 7/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8511433 | 0.99 | KARS1 (0.45) | KARS1HTR2CCTSSPIM1CTSK | |
| SCHEMBL8510804 | 0.87 | PIM1 (0.42) | KARS1PIM1PRKCAPRKCQPRKCD | |
| Hydrochloric Acid SCHEMBL8514424 | 0.86 | PIM1 (0.41) | KARS1PIM1PRKCAPRKCQPRKCD | |
| SCHEMBL8515290 | 0.85 | KARS1 (0.45) | KARS1HTR2CPIM1PRKCAPRKCQ | |
| Hydrochloric Acid SCHEMBL8512524 | 0.84 | KARS1 (0.44) | KARS1HTR2CPIM1PRKCAPRKCQ | |
| SCHEMBL8514744 | 0.83 | S1PR1 (0.41) | KARS1PIM1PRKCAPRKCQPRKCD | |
| Hydrochloric Acid SCHEMBL8512940 | 0.82 | S1PR1 (0.41) | KARS1PIM1PRKCAPRKCQPRKCD | |
| SCHEMBL8514027 | 0.82 | CKS1B (0.46) | — | |
| SCHEMBL8510230 | 0.77 | KARS1 (0.34) | KARS1HTR2CPIM1PIM3PIM2 | |
| SCHEMBL4457426 | 0.73 | HTR3E (0.49) | KARS1PIM1PRKCAPRKCQPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069852-A1 | PHARMACEUTICAL COMPOUNDS AS INHIBITORS OF SPHINGOSINE KINASE | ALMAC DISCOVERY LIMITED (GB) | 2012-05-31 | — | — | WO | claimed |