Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13516645 | 0.92 | ALDH1A1 (0.55) | SMN1; SMN2NPC1MEN1KMT2AMAPT | |
| SCHEMBL4994157 | 0.85 | ALDH1A1 (0.51) | SMN1; SMN2NPC1MEN1KMT2AMAPT | |
| SCHEMBL11515591 | 0.84 | TSHR (0.66) | SMN1; SMN2NPC1MEN1KMT2AMAPT | |
| SCHEMBL8515949 | 0.82 | POLB (0.56) | SMN1; SMN2NPC1MAPTRAB9AHPGD | |
| SCHEMBL69454 | 0.82 | LOXL2 (0.70) | SMN1; SMN2NPC1MEN1KMT2AMAPT | |
| SCHEMBL28902573 | 0.81 | LOXL2 (0.56) | SMN1; SMN2NPC1MEN1KMT2AMAPT | |
| SCHEMBL14543572 | 0.81 | KMT2A (0.50) | SMN1; SMN2NPC1MEN1KMT2AMAPT | |
| SCHEMBL19073513 | 0.80 | KMT2A (0.49) | SMN1; SMN2NPC1MEN1KMT2AMAPT | |
| SCHEMBL16155876 | 0.79 | TDP1 (0.77) | MEN1KMT2AMAPTLOXL2CA12 | |
| SCHEMBL572 | 0.79 | KMT2A (0.58) | NPC1MEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |