Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 4/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | FCER2 | P06734 | 1/20 | 0.39 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pabetan SCHEMBL29894618 | 0.79 | NPY4R (0.46) | FCER2KISS1R | |
| Pabetan SCHEMBL21571465 | 0.79 | NPY4R (0.46) | FCER2KISS1R | |
| Pabetan SCHEMBL14928984 | 0.79 | NPY4R (0.46) | FCER2KISS1R | |
| Pabetan SCHEMBL4546522 | 0.79 | NPY4R (0.46) | FCER2KISS1R | |
| SCHEMBL26025959 | 0.78 | OPRK1 (0.49) | OPRK1SIRT1SSTR3 | |
| SCHEMBL26015644 | 0.76 | SSTR3 (0.47) | OPRK1SIRT1SSTR3 | |
| SCHEMBL8358632 | 0.76 | OPRD1 (0.49) | OPRD1OPRK1KISS1R | |
| Pabetan SCHEMBL23784701 | 0.76 | MC4R (0.56) | OPRK1TACR1 | |
| Pabetan SCHEMBL1738816 | 0.76 | MC4R (0.56) | OPRK1TACR1 | |
| Pabetan SCHEMBL29359620 | 0.76 | MC4R (0.56) | OPRK1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |