Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.49 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.45 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.44 |
| ▸ | NPY4R | P50391 | 5/20 | 0.44 |
| ▸ | NPY1R | P25929 | 3/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 2/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8362723 | 0.85 | LNPEP (0.46) | LNPEPOPRK1ERAP2 | |
| SCHEMBL7860762 | 0.82 | LNPEP (0.47) | LNPEPOPRK1ERAP2 | |
| Trifluoroacetic Acid SCHEMBL7860829 | 0.79 | LNPEP (0.44) | LNPEPOPRK1ERAP2 | |
| SCHEMBL8515919 | 0.76 | OPRD1 (0.40) | OPRD1KISS1ROPRK1 | |
| SCHEMBL7860804 | 0.75 | MMP2 (0.47) | — | |
| SCHEMBL7850357 | 0.74 | MMP2 (0.51) | LNPEPOPRK1ERAP2 | |
| SCHEMBL7859103 | 0.74 | LNPEP (0.52) | LNPEPERAP2 | |
| SCHEMBL30519188 | 0.73 | OPRD1 (0.65) | OPRD1OPRK1OPRM1 | |
| Trifluoroacetic Acid SCHEMBL7859146 | 0.72 | LNPEP (0.48) | LNPEPERAP2 | |
| SCHEMBL25495974 | 0.71 | IDE (0.38) | LNPEPERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |