Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22018747 | 0.81 | NOTUM (0.49) | NOTUMALDH1A1NPC1LMNAMEN1 | |
| SCHEMBL11307322 | 0.81 | NOTUM (0.49) | NOTUMALDH1A1NPC1LMNAMEN1 | |
| SCHEMBL24201529 | 0.80 | NOTUM (0.47) | NOTUMALDH1A1NPC1LMNAMEN1 | |
| SCHEMBL5218354 | 0.78 | NOTUM (0.41) | NOTUMALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL11582790 | 0.77 | DRD2 (0.41) | NOTUMALDH1A1NPC1LMNAPKM | |
| SCHEMBL28314815 | 0.75 | NOTUM (0.42) | NOTUMNPC1MEN1KMT2ACHRM2 | |
| Formamide SCHEMBL4376802 | 0.75 | NOTUM (0.50) | NOTUMALDH1A1NPC1LMNAMEN1 | |
| SCHEMBL29740237 | 0.75 | NOTUM (0.43) | NOTUMALDH1A1NPC1LMNAMEN1 | |
| SCHEMBL22292629 | 0.75 | NOTUM (0.53) | NOTUMALDH1A1NPC1LMNAMEN1 | |
| SCHEMBL1517961 | 0.74 | NOTUM (0.49) | NOTUMALDH1A1LMNAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108774147-B | N-aryl formamide prepared by taking bromodifluoroacetic acid ethyl ester as formylation reagent | 温州大学 | 2021-01-08 | — | — | CN | disclosed |
| CN-108774147-A | A kind of N- aryl carboxamides prepared as formylation reagent using bromo difluoro acetate ethyl ester | 温州大学 | 2018-11-09 | — | — | CN | disclosed |
| US-8759461-B2 | Post metallocene-type transition metal compounds | LG CHEM, LTD. (KR) | 2014-06-24 | — | — | US | disclosed |
| CN-102548962-B | Novel post metallocene-type transition metal compound | LG CHEMICAL LTD | 2014-06-18 | — | — | CN | disclosed |
| EP-2457894-B1 | NOVEL POST METALLOCENE-TYPE TRANSITION METAL COMPOUND | LG CHEMICAL LTD (KR) | 2014-01-22 | — | — | EP | disclosed |
| US-20120196994-A1 | NOVEL POST METALLOCENE-TYPE TRANSITION METAL COMPOUNDS | LG CHEM, LTD. (KR) | 2012-08-02 | — | — | US | disclosed |
| CN-102548962-A | Novel post metallocene-type transition metal compound | LG CHEMICAL LTD | 2012-07-04 | — | — | CN | disclosed |
| EP-2457894-A2 | NOVEL POST METALLOCENE-TYPE TRANSITION METAL COMPOUND | LG Chem, Ltd. (KR) | 2012-05-30 | — | — | EP | disclosed |
| US-5130442-A | Compounds for forming color in recording material based on acid developers | BAYER AKTIENGESELLSCHAFT (DE) | 1992-07-14 | — | — | US | disclosed |
| EP-0431425-A2 | Chromogen enamine compounds, their preparation and use as colour formers | BAYER AG (DE) | 1991-06-12 | — | — | EP | disclosed |
| US-4145537-A | BENZOTHIAZOLIUM DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-20 | — | — | US | disclosed |
| US-4110070-A | QUATERNIZING INDOLENINE METHINE COMPOUND ON FIBERS TO FORM CATIONIC DYE | HODOGAYA CHEMICAL CO., LTD. (JP) | 1978-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196994-A1 | NOVEL POST METALLOCENE-TYPE TRANSITION METAL COMPOUNDS | ZC3HAV1L, ZKSCAN2, ZC3H18 | NOTUM 638/4885ALDH1A1 3061/4885NPC1 3581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.