Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 8/20 | 0.49 |
| ▸ | CTSS | P25774 | 5/20 | 0.47 |
| ▸ | CTSK | P43235 | 5/20 | 0.47 |
| ▸ | CTSB | P07858 | 3/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | P4HB | P07237 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357815 | 0.90 | CTSL (0.51) | CTSLCTSSCTSKCTSBREN | |
| SCHEMBL7354760 | 0.84 | CTSK (0.53) | CTSLCTSSCTSKCTSBPPARG | |
| SCHEMBL3821796 | 0.80 | PPARA (0.60) | CTSLCTSSCTSKCTSBREN | |
| SCHEMBL6808534 | 0.77 | REN (0.63) | CTSLCTSSCTSKCTSBREN | |
| SCHEMBL6808536 | 0.77 | REN (0.63) | CTSLCTSSCTSKCTSBREN | |
| SCHEMBL18830579 | 0.76 | CTSS (0.61) | CTSLCTSSCTSKCTSBPPARG | |
| SCHEMBL23734346 | 0.75 | CTSS (0.65) | CTSLCTSSCTSKCTSBREN | |
| SCHEMBL3008254 | 0.75 | HDAC8 (0.59) | CTSLCTSSCTSKCTSBACE | |
| SCHEMBL3008259 | 0.75 | HDAC8 (0.59) | CTSLCTSSCTSKCTSBACE | |
| SCHEMBL1196169 | 0.74 | MAPT (0.59) | CTSLCTSSCTSKCTSBACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756625-A4 | IRREVERSIBLE CYSTEINE PROTEASE INHIBITORS CONTAINING VINYL GROUPS CONJUGATED TO ELECTRON WITHDRAWING GROUPS | ARRIS PHARM CORP (US) | 1999-07-28 | — | — | EP | disclosed |
| EP-0756625-A1 | IRREVERSIBLE CYSTEINE PROTEASE INHIBITORS CONTAINING VINYL GROUPS CONJUGATED TO ELECTRON WITHDRAWING GROUPS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1997-02-05 | — | — | EP | disclosed |