Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 10/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 10/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 7/20 | 0.33 |
| ▸ | CASP7 | P55210 | 7/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | HBB | P68871 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516080 | 0.93 | USP2 (0.35) | USP2CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL8365344 | 0.92 | ATM (0.39) | USP2CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL8517087 | 0.91 | USP2 (0.34) | USP2CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL8516687 | 0.89 | USP2 (0.33) | USP2CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL8367898 | 0.85 | CTSB (0.31) | USP2CYP1A2CYP3A4CASP1CASP7 | |
| SCHEMBL8516657 | 0.85 | PDE4B (0.32) | POLB | |
| SCHEMBL8365258 | 0.84 | ALDH1A1 (0.37) | USP2CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8516518 | 0.83 | USP2 (0.37) | USP2CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL8516861 | 0.83 | ALDH1A1 (0.36) | USP2CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8515856 | 0.82 | CA12 (0.38) | USP2CYP1A2CYP3A4CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |