Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | CFTR | P13569 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | OGFRL1 | Q5TC84 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8516014 | 0.92 | CA12 (0.42) | KMT2AMEN1USP2CFTRALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8516085 | 0.90 | KMT2A (0.40) | KMT2AMEN1USP2PTGDR2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8516758 | 0.87 | PTGDR2 (0.39) | KMT2AMEN1USP2PTGDR2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8516225 | 0.85 | BRD4 (0.39) | KMT2AMEN1CFTRALDH1A1LMNA | |
| Trifluoroacetic Acid SCHEMBL8516143 | 0.84 | PAX8 (0.44) | CFTRLMNACNR2CA12CA1 | |
| Trifluoroacetic Acid SCHEMBL8516996 | 0.84 | ALDH1A1 (0.42) | KMT2AMEN1USP2CFTRALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8362794 | 0.83 | CFTR (0.42) | KMT2AMEN1USP2PTGDR2CFTR | |
| Trifluoroacetic Acid SCHEMBL8365308 | 0.82 | CFTR (0.40) | KMT2AMEN1USP2PTGDR2CFTR | |
| Trifluoroacetic Acid SCHEMBL8368543 | 0.82 | CFTR (0.42) | KMT2AMEN1USP2CFTRALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8516818 | 0.81 | CFTR (0.42) | KMT2AMEN1USP2CFTRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | claimed |
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |