Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 3/20 | 0.40 |
| ▸ | CAMK2D | Q13557 | 7/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8515918 | 0.95 | IGF1R (0.39) | IGF1RCAMK2DMAOBPPARGPPARD | |
| SCHEMBL8516344 | 0.91 | CAMK2D (0.40) | CAMK2DKDR | |
| SCHEMBL8516793 | 0.88 | CAMK2D (0.48) | CAMK2DKDR | |
| SCHEMBL8515897 | 0.88 | CAMK2D (0.44) | CAMK2DKDR | |
| SCHEMBL8365275 | 0.87 | CAMK2D (0.37) | CAMK2DKDR | |
| SCHEMBL8362233 | 0.87 | CAMK2D (0.38) | IGF1RCAMK2DMAOBEGFRFLT4 | |
| SCHEMBL7658242 | 0.86 | MAOB (0.38) | IGF1RCAMK2DMAOBEGFRFLT4 | |
| SCHEMBL8516977 | 0.86 | CAMK2D (0.46) | CAMK2D | |
| SCHEMBL8516993 | 0.85 | CAMK2D (0.37) | CAMK2DKDR | |
| SCHEMBL7657833 | 0.84 | MAOB (0.36) | IGF1RMAOBEGFRFLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | claimed |
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |