Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 9/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | EDNRB | P24530 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516793 | 0.88 | CAMK2D (0.48) | CAMK2DCNR2KDRGSK3B | |
| SCHEMBL8516344 | 0.88 | CAMK2D (0.40) | CAMK2DCNR2KDRGSK3B | |
| SCHEMBL8515897 | 0.88 | CAMK2D (0.44) | CAMK2DKDRGSK3B | |
| SCHEMBL8516409 | 0.87 | TP53 (0.43) | TP53EDNRBMAPTRXFP1 | |
| SCHEMBL8516957 | 0.87 | CAMK2D (0.37) | CAMK2DTP53EDNRBKDM4EALDH1A1 | |
| SCHEMBL8516977 | 0.86 | CAMK2D (0.46) | CAMK2DCNR2 | |
| SCHEMBL7659720 | 0.85 | CAMK2D (0.36) | CAMK2DTP53KDM4EALDH1A1CYP1A2 | |
| SCHEMBL8516735 | 0.85 | IGF1R (0.40) | CAMK2DKDR | |
| SCHEMBL8365275 | 0.84 | CAMK2D (0.37) | CAMK2DCNR2KDRGSK3B | |
| SCHEMBL8516619 | 0.84 | ASH1L (0.43) | CAMK2DTDP1GSK3BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | claimed |
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |