SCHEMBL8516622

SCHEMBL8516622

O=S(=O)(O)c1cc(-c2ccc(O)cc2)cc(S(=O)(=O)O)c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.52
ABL1 P00519 3/20 0.48
ABCB1 P08183 3/20 0.48
BCR P11274 3/20 0.48
LMNA P02545 2/20 0.46
ESR2 Q92731 4/20 0.46
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
NSD2 O96028 1/20 0.41
MMP14 P50281 1/20 0.41
CASP6 P55212 1/20 0.41
ALOX5 P09917 1/20 0.40
HSD17B10 Q99714 2/20 0.40
HPGD P15428 1/20 0.40
HIF1A Q16665 1/20 0.40
PGAM1 P18669 1/20 0.40
MMP3 P08254 1/20 0.39
BCL2L1 Q07817 1/20 0.39
HSD17B1 P14061 1/20 0.39
HSD17B2 P37059 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5539966 0.87 HSD17B10 (0.45) LMNAMEN1KMT2ANSD2MMP14
SCHEMBL8367613 0.83 PGAM1 (0.47) MEN1KMT2AHSD17B10HPGDPGAM1
SCHEMBL31556893 0.82 LMNA (0.54) ESR1LMNAESR2MEN1KMT2A
SCHEMBL8516780 0.82 LMNA (0.54) ESR1LMNAESR2MEN1KMT2A
SCHEMBL4968560 0.78 HSD17B10 (0.40) LMNANSD2MMP14CASP6HSD17B10
SCHEMBL8516738 0.77 ESR2 (0.46) ESR1LMNAESR2MEN1KMT2A
SCHEMBL3235461 0.77 HSD17B10 (0.45) LMNANSD2MMP14CASP6HSD17B10
SCHEMBL5546794 0.77 ALDH1A1 (0.39) LMNAESR2MEN1KMT2ANSD2
SCHEMBL8516704 0.76 TYR (0.46) ESR1LMNAESR2MEN1KMT2A
SCHEMBL8516683 0.76 LMNA (0.48) ESR1ABL1ABCB1BCRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714785-B1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI CHEMICALS INC (JP) 1999-01-07 EP disclosed
US-5647896-A MULTIVALENT SALT OF A SALICYLIC ACID DERIVATIVE, SULFONATED PHENOL MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
EP-0714785-A1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-06-05 EP disclosed