SCHEMBL8516780

SCHEMBL8516780

O=S(=O)(O)c1cc(-c2ccc(O)cc2)ccc1O

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.54
HPGD P15428 1/20 0.54
HIF1A Q16665 1/20 0.54
HSD17B10 Q99714 1/20 0.54
ALOX5 P09917 1/20 0.54
EGFR P00533 1/20 0.47
PTGS1 P23219 1/20 0.46
ESR1 P03372 10/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
ESR2 Q92731 8/20 0.44
PELI1 Q96FA3 1/20 0.43
HSD17B1 P14061 2/20 0.43
HSD17B2 P37059 2/20 0.43
POLB P06746 1/20 0.42
GAA P10253 1/20 0.42
GFER P55789 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31556893 1.00 LMNA (0.54) LMNAHPGDHIF1AHSD17B10ALOX5
SCHEMBL1535883 0.92 HSD17B10 (0.52) LMNAHPGDHIF1AHSD17B10ALOX5
Potassium SCHEMBL30364442 0.90 HSD17B10 (0.50) LMNAHPGDHIF1AHSD17B10ALOX5
SCHEMBL28993725 0.90 HSD17B10 (0.50) LMNAHPGDHIF1AHSD17B10ALOX5
SCHEMBL8367501 0.86 ALOX5 (0.55) LMNAHPGDHIF1AHSD17B10ALOX5
Dobesilic Acid SCHEMBL29389625 0.83 LMNA (0.72) LMNAHPGDHIF1AHSD17B10ALOX5
Dobesilic Acid SCHEMBL232087 0.83 LMNA (0.72) LMNAHPGDHIF1AHSD17B10ALOX5
SCHEMBL8516622 0.82 ESR1 (0.52) LMNAHPGDHIF1AHSD17B10ALOX5
Dobesilic Acid SCHEMBL10589964 0.81 HSD17B10 (0.70) LMNAHPGDHIF1AHSD17B10ALOX5
Dobesilic Acid SCHEMBL78224 0.81 LMNA (0.70) LMNAHPGDHIF1AHSD17B10ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230275251-A1 CROSSOVER RESISTANT MATERIALS FOR AQUEOUS ORGANIC REDOX FLOW BATTERIES UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2023-08-31 US disclosed
US-11646434-B2 Crossover resistant materials for aqueous organic redox flow batteries UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2023-05-09 US disclosed
EP-0714785-B1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI CHEMICALS INC (JP) 1999-01-07 EP disclosed
US-5647896-A MULTIVALENT SALT OF A SALICYLIC ACID DERIVATIVE, SULFONATED PHENOL MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
EP-0714785-A1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-06-05 EP disclosed
US-4403087-A Polycarbonates chain terminated with sulfonic acid salt containing phenols GENERAL ELECTRIC COMPANY (US) 1983-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230275251-A1 CROSSOVER RESISTANT MATERIALS FOR AQUEOUS ORGANIC REDOX FLOW BATTERIES SLC25A21, SLC25A11, SLC26A3 LMNA 3543/4885HPGD 1005/4885HIF1A 4842/4885
US-11646434-B2 Crossover resistant materials for aqueous organic redox flow batteries SLC25A21, SLC25A11, SLC26A3 LMNA 3543/4885HPGD 1005/4885HIF1A 4842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.