Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8653085 | 0.77 | CYP19A1 (0.41) | ALDH1A1HPGDKDM4EHTTCYP19A1 | |
| SCHEMBL4743450 | 0.74 | ACHE (0.55) | ALDH1A1CYP19A1LMNA | |
| SCHEMBL5951282 | 0.74 | CYP19A1 (0.38) | ALDH1A1HPGDCYP19A1 | |
| SCHEMBL7752270 | 0.72 | ACHE (0.53) | ALDH1A1HPGDKDM4ECYP1A2CYP2C19 | |
| SCHEMBL874650 | 0.72 | METAP1 (0.57) | CYP19A1 | |
| SCHEMBL24209598 | 0.71 | CYP19A1 (0.36) | ALDH1A1HPGDKDM4ECYP19A1GLA | |
| SCHEMBL8903120 | 0.69 | CYP19A1 (0.36) | ALDH1A1KDM4ECYP1A2CYP2C19CYP19A1 | |
| SCHEMBL3718760 | 0.67 | THRA (0.39) | KDM4ECYP19A1MAPTHSD17B10 | |
| SCHEMBL5951960 | 0.67 | HTR7 (0.44) | ALDH1A1HPGDKDM4EHTTSMN1; SMN2 | |
| SCHEMBL5952885 | 0.65 | HTR7 (0.45) | ALDH1A1HPGDCYP1A2CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861522-A | Production of bridged metallocene complexes and intermediates therefor | ALBEMARLE CORPORATION (US) | 1999-01-19 | — | — | US | claimed |
| US-5710299-A | Production of bridged metallocene complexes and intermediates therefor | ALBEMARLE CORPORATION (US) | 1998-01-20 | — | — | US | claimed |