Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 15/20 | 0.59 |
| ▸ | CA9 | Q16790 | 15/20 | 0.59 |
| ▸ | CA12 | O43570 | 14/20 | 0.59 |
| ▸ | CA1 | P00915 | 12/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9097181 | 0.94 | LMNA (0.70) | LMNAKDM4EALDH1A1CA2CA9 | |
| SCHEMBL8193969 | 0.92 | LMNA (0.68) | LMNAKDM4EALDH1A1CA2CA9 | |
| SCHEMBL18118191 | 0.92 | LMNA (0.68) | LMNAKDM4EALDH1A1CA2CA9 | |
| SCHEMBL18118187 | 0.90 | LMNA (0.70) | LMNAKDM4EALDH1A1CA2CA9 | |
| SCHEMBL7652825 | 0.81 | LMNA (0.54) | LMNAKDM4EALDH1A1MAPK1HTT | |
| Hydrochloric Acid SCHEMBL7652831 | 0.81 | LMNA (0.54) | LMNAKDM4EALDH1A1MAPK1HTT | |
| Hydrochloric Acid SCHEMBL7652732 | 0.80 | LMNA (0.53) | LMNAKDM4EALDH1A1MAPK1HTT | |
| SCHEMBL7652722 | 0.80 | LMNA (0.53) | LMNAKDM4EALDH1A1CA2CA9 | |
| SCHEMBL11548897 | 0.79 | ALDH1A1 (0.58) | LMNAKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5722180 | 0.79 | ALDH1A1 (0.66) | LMNAKDM4EALDH1A1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877018-B1 | Sulfonylaminocarboxylic acids | AVENTIS PHARMA GMBH (DE) | 2003-05-02 | — | — | EP | disclosed |