Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652825 | 0.98 | LMNA (0.54) | LMNASMN1; SMN2HTTMAPK1MAPT | |
| SCHEMBL9582446 | 0.94 | LMNA (0.58) | LMNASMN1; SMN2HTTMAPK1MAPT | |
| SCHEMBL9581858 | 0.94 | LMNA (0.58) | LMNASMN1; SMN2HTTMAPK1MAPT | |
| SCHEMBL3176219 | 0.93 | LMNA (0.59) | LMNASMN1; SMN2HTTMAPK1MAPT | |
| SCHEMBL6561315 | 0.84 | PKM (0.58) | HTTMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL17902921 | 0.83 | ALDH1A1 (0.63) | LMNAHTTALDH1A1KDM4EUSP2 | |
| SCHEMBL17899709 | 0.83 | KMT2A (0.50) | SMN1; SMN2HTTMAPTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL7652732 | 0.82 | LMNA (0.53) | LMNASMN1; SMN2HTTMAPK1MAPT | |
| SCHEMBL31013493 | 0.80 | ALDH1A1 (0.62) | LMNASMN1; SMN2HTTMAPK1MAPT | |
| Hydrochloric Acid SCHEMBL7652831 | 0.80 | LMNA (0.54) | LMNASMN1; SMN2HTTMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339092-B1 | FOR THERAPY RHEUMATOID ARTHRITIS, ARTHROSIS, TUMOUR INVASION AND GROWTH, INCLUDING MALIGNANT SPREAD AND THE FORMATION OF METASTASES, ULCERATIONS, ATHEROSCLEROSIS | ADIR ET COMPAGNIE (FR) | 2002-01-15 | — | — | US | disclosed |