Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPM1 | P06748 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8516597 | 0.93 | BRD4 (0.44) | CNR2PAX8BRD4PDE4APDE4B | |
| Trifluoroacetic Acid SCHEMBL8516454 | 0.88 | CNR2 (0.41) | CNR2PAX8BRD4GHSRACP1 | |
| Trifluoroacetic Acid SCHEMBL8365272 | 0.84 | BRD4 (0.40) | BRD4PARP1PARP2GHSRLMNA | |
| Trifluoroacetic Acid SCHEMBL8517048 | 0.84 | PAX8 (0.46) | CNR2PAX8PDE4APDE4BPDE4C | |
| Trifluoroacetic Acid SCHEMBL8516922 | 0.82 | LMNA (0.39) | CNR2PAX8BRD4PDE4APDE4B | |
| Trifluoroacetic Acid SCHEMBL4687029 | 0.82 | BRD4 (0.51) | BRD4PDE4APDE4BPDE4CPDE4D | |
| Trifluoroacetic Acid SCHEMBL8367841 | 0.81 | LMNA (0.38) | CNR2PAX8BRD4PDE4APDE4B | |
| Trifluoroacetic Acid SCHEMBL8516040 | 0.80 | LMNA (0.37) | CNR2PAX8BRD4PDE4APDE4B | |
| Trifluoroacetic Acid SCHEMBL8366749 | 0.80 | LMNA (0.41) | CNR2PAX8BRD4PDE4APDE4B | |
| Trifluoroacetic Acid SCHEMBL8368507 | 0.78 | BRD4 (0.43) | CNR2BRD4GHSRACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | claimed |
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |