Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 4/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPM1 | P06748 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8516160 | 0.93 | PAX8 (0.47) | PAX8CNR2POLBPDE4APDE4B | |
| Trifluoroacetic Acid SCHEMBL8367881 | 0.90 | CYP1A2 (0.41) | PAX8CNR2PDE4APDE4BPDE4C | |
| Trifluoroacetic Acid SCHEMBL8516143 | 0.87 | PAX8 (0.44) | PAX8CNR2POLBPDE4APDE4B | |
| Trifluoroacetic Acid SCHEMBL8517047 | 0.84 | CNR2 (0.40) | PAX8CNR2POLBPDE4APDE4B | |
| Trifluoroacetic Acid SCHEMBL8516758 | 0.83 | PTGDR2 (0.39) | PAX8PDE4BPDE4DLMNAMEN1 | |
| Trifluoroacetic Acid SCHEMBL8515754 | 0.82 | CYP1A2 (0.40) | CNR2POLBCNR1LMNAMEN1 | |
| Trifluoroacetic Acid SCHEMBL8365282 | 0.82 | CYP1A2 (0.44) | LMNAMEN1KMT2AUSP2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8516922 | 0.81 | LMNA (0.39) | PAX8CNR2POLBPDE4APDE4B | |
| Trifluoroacetic Acid SCHEMBL8367899 | 0.81 | LMNA (0.44) | PAX8CNR2POLBPDE4APDE4B | |
| Trifluoroacetic Acid SCHEMBL8367841 | 0.80 | LMNA (0.38) | PAX8CNR2POLBPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | claimed |
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |