Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN7A | Q01118 | 10/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 10/20 | 0.55 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL850901 | 0.83 | GPR119 (0.49) | SCN7AKCNH2SCN9AF10PRSS1 | |
| SCHEMBL8509596 | 0.79 | F10 (0.53) | F10PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL851787 | 0.77 | F2 (0.56) | SCN9AF10PRSS1PRSS2PRSS3 | |
| SCHEMBL850860 | 0.76 | SIGMAR1 (0.43) | SCN7AKCNH2SCN9AF10PRSS1 | |
| SCHEMBL851402 | 0.75 | F10 (0.53) | SCN9AF10PRSS1PRSS2PRSS3 | |
| SCHEMBL851451 | 0.74 | SCN9A (0.63) | SCN7AKCNH2SCN9APRSS1PRSS2 | |
| SCHEMBL852030 | 0.74 | F10 (0.48) | SCN9AF10POLBSCN8ASCN10A | |
| SCHEMBL8509642 | 0.73 | F10 (0.58) | F10POLB | |
| SCHEMBL851176 | 0.72 | F10 (0.49) | SCN9AF10PRSS1PRSS2PRSS3 | |
| SCHEMBL851888 | 0.71 | HRH3 (0.54) | SCN7AKCNH2SCN9AHRH3SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140200225-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2014-07-17 | — | — | US | disclosed |
| US-8722930-B2 | Protease inhibitors | ORION CORPORATION (FI) | 2014-05-13 | — | — | US | disclosed |
| US-20120136002-A1 | PROTEASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2012-05-31 | — | — | US | disclosed |
| EP-2432556-A1 | PROTEASE INHIBITORS | Orion Corporation (FI) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133748-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200225-A1 | PROTEASE INHIBITORS | SERPINB1, TMPRSS15, PRSS1 | SCN7A 2970/4885KCNH2 4297/4885SCN9A 1907/4885 |
| US-20120136002-A1 | PROTEASE INHIBITORS | SERPINB1, TMPRSS15, PRSS1 | SCN7A 2970/4885KCNH2 4297/4885SCN9A 1907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.