SCHEMBL8517210

SCHEMBL8517210

NNc1cccc(C(=O)NCCS(=O)(=O)CCO)c1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
HSD17B10 Q99714 1/20 0.42
LOX P28300 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
GAA P10253 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
LMNA P02545 1/20 0.39
KDM1A O60341 1/20 0.39
PAX8 Q06710 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8517143 0.86 KDM4E (0.45) MEN1KMT2AHSD17B10LOXSMN1; SMN2
SCHEMBL15044749 0.81 NPC1 (0.57) MEN1KMT2AHSD17B10SMN1; SMN2GAA
SCHEMBL9317018 0.80 PAX8 (0.45) MEN1KMT2AHSD17B10SMN1; SMN2GAA
SCHEMBL537946 0.75 HPGD (0.56) LOXSMN1; SMN2GAALMNAPAX8
SCHEMBL9341679 0.75 SMN1; SMN2 (0.45) MEN1KMT2AHSD17B10SMN1; SMN2L3MBTL1
SCHEMBL3055037 0.75 ALDH1A1 (0.63) MEN1KMT2ASMN1; SMN2GAAL3MBTL1
SCHEMBL8516912 0.75 LMNA (0.50) MEN1KMT2ALOXLMNA
SCHEMBL9317025 0.74 TP53 (0.39) MEN1KMT2AHSD17B10GAALMNA
SCHEMBL537132 0.74 NPC1 (0.51) MEN1KMT2AHSD17B10SMN1; SMN2GAA
Hydrochloric Acid SCHEMBL8696519 0.74 SMN1; SMN2 (0.44) MEN1KMT2AHSD17B10SMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0586331-B1 Process for dyeing synthetic polyamid fibre materials CIBA GEIGY AG (CH) 1999-01-07 EP disclosed
US-5356440-A Fiber-reactive dyes containing only one sulfo group CIBA-GEIGY CORPORATION (US) 1994-10-18 US disclosed
EP-0586331-A2 Process for dyeing synthetic polyamid fibre materials CIBA-GEIGY AG (CH) 1994-03-09 EP disclosed