Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.49 |
| ▸ | CA2 | P00918 | 5/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337533 | 0.86 | LMNA (0.49) | LMNAKDM4ETSHRMAPTHIF1A | |
| Hydrochloric Acid SCHEMBL8692099 | 0.85 | LMNA (0.50) | LMNAKDM4ETSHRMAPTHIF1A | |
| SCHEMBL15044687 | 0.84 | MMP13 (0.57) | LMNAALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL8517143 | 0.82 | KDM4E (0.45) | KDM4EALDH1A1KMT2AMEN1LOX | |
| SCHEMBL28879276 | 0.82 | LMNA (0.46) | LMNAKDM4ETSHRMAPTHIF1A | |
| SCHEMBL12040903 | 0.82 | KDM4E (0.54) | LMNAKDM4ETSHRMAPTHIF1A | |
| SCHEMBL8516959 | 0.82 | HDAC3 (0.51) | LMNAKDM4EALDH1A1CA1CA2 | |
| SCHEMBL853629 | 0.81 | KDM4E (0.61) | LMNAKDM4ETSHRMAPTHIF1A | |
| SCHEMBL8517331 | 0.80 | HDAC3 (0.44) | KDM4EMAPTALDH1A1CA1CA2 | |
| SCHEMBL9344489 | 0.79 | KDM4E (0.68) | LMNAKDM4ETSHRMAPTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586331-B1 | Process for dyeing synthetic polyamid fibre materials | CIBA GEIGY AG (CH) | 1999-01-07 | — | — | EP | disclosed |
| US-5356440-A | Fiber-reactive dyes containing only one sulfo group | CIBA-GEIGY CORPORATION (US) | 1994-10-18 | — | — | US | disclosed |
| EP-0586331-A2 | Process for dyeing synthetic polyamid fibre materials | CIBA-GEIGY AG (CH) | 1994-03-09 | — | — | EP | disclosed |