Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 10/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1537949 | 0.89 | FDPS (0.38) | OPRM1FDPSGGPS1SPHK1 | |
| Ammonia Solution, Strong SCHEMBL27932619 | 0.86 | FDPS (0.34) | OPRM1FDPSGGPS1CA1SPHK1 | |
| SCHEMBL4249951 | 0.86 | LMNA (0.43) | FDPSGGPS1SPHK1LMNA | |
| SCHEMBL9712291 | 0.86 | GPR84 (0.37) | FDPSGGPS1SPHK1LMNA | |
| SCHEMBL4454720 | 0.86 | SPHK1 (0.41) | OPRM1FDPSGGPS1SPHK1LMNA | |
| Hydrochloric Acid SCHEMBL5604452 | 0.85 | SPHK1 (0.40) | OPRM1FDPSGGPS1SPHK1LMNA | |
| SCHEMBL25232433 | 0.81 | TSHR (0.43) | FDPSSPHK1LMNATP53 | |
| SCHEMBL9700851 | 0.80 | FDPS (0.38) | FDPSGGPS1 | |
| SCHEMBL28056385 | 0.80 | OPRM1 (0.39) | OPRM1FDPSGGPS1CA1SPHK1 | |
| SCHEMBL9715537 | 0.80 | SPHK1 (0.42) | OPRM1FDPSGGPS1SPHK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874436-A | EFFECTIVE IN INHIBITING THE ACTION OF A BACTERIAL HISTIDINE PROTEIN KINASE; USEFUL AGAINST ANTIBIOTIC RESISTANT ORGANISMS | DEMERS JAMES P (US) | 1999-02-23 | — | — | US | disclosed |
| WO-1997048676-A1 | TRIPHENYLALKYL ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-24 | — | — | WO | disclosed |
| US-5643950-A | INHIBITORS OF A BACTERIAL HISTIDINE PROTEIN KINASE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |