SCHEMBL8517818

SCHEMBL8517818

COc1ccccc1C(c1ccccc1)(c1ccccc1OC)C(O)[C@H]1O[C@@](CCCNC(=O)C(F)(F)F)(n2ccc(=O)[nH]c2=O)C[C@@H]1O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DUT P33316 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9498388 0.85
SCHEMBL8932014 0.82 TK2 (0.30)
SCHEMBL9494704 0.77 DUT (0.31) DUT
SCHEMBL8932101 0.74 HCRTR1 (0.32)
SCHEMBL7599465 0.73 TK1 (0.37)
SCHEMBL9497663 0.73 DUT (0.32) DUT
SCHEMBL7603167 0.73 TK1 (0.37)
SCHEMBL7599691 0.72 TK1 (0.36)
SCHEMBL8932016 0.72 TK2 (0.32)
SCHEMBL8932073 0.71 TK1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0563010-B1 Method of preparation of nucleosides NOVARTIS AG (CH) 1999-04-28 EP disclosed