Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.46 |
| ▸ | LPL | P06858 | 2/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 5/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8517452 | 0.84 | LPL (0.39) | LPLLIPGCA2MGLLPLK1 | |
| SCHEMBL6401559 | 0.78 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1MAPTCNR1 | |
| SCHEMBL2553722 | 0.73 | ALDH1A1 (0.54) | THRBLPLLIPGCA2THRA | |
| SCHEMBL8077541 | 0.73 | THRB (0.52) | THRBLPLLIPGCA2THRA | |
| SCHEMBL142480 | 0.71 | LPL (0.62) | THRBLPLLIPGCA2MGLL | |
| SCHEMBL463323 | 0.70 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL8077551 | 0.69 | THRB (0.48) | THRBLPLLIPGTHRAKMT2A | |
| SCHEMBL52038 | 0.69 | ALDH1A1 (0.52) | THRBLPLLIPGCA2THRA | |
| Water SCHEMBL28941509 | 0.68 | LPL (0.59) | THRBLPLLIPGCA2MGLL | |
| SCHEMBL9839848 | 0.68 | LPL (0.59) | THRBLPLLIPGCA2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0905172-A1 | POLYSILANES AND POSITIVE HOLE TRANSPORTING MATERIALS | OSAKA GAS CO., LTD. (JP) | 1999-03-31 | — | — | EP | disclosed |