Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518994 | 0.98 | LMNA (0.42) | LMNAALDH1A1CYP3A4MEN1MITF | |
| SCHEMBL11559279 | 0.94 | LMNA (0.40) | LMNAALDH1A1MEN1KMT2AHTR2C | |
| SCHEMBL542283 | 0.87 | NOS2 (0.39) | HTR2CELANEPRCP | |
| SCHEMBL11560266 | 0.84 | TSHR (0.38) | LMNATSHRELANEPRCP | |
| Succinic Acid SCHEMBL15323280 | 0.82 | PRCP (0.38) | LMNAALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL10885146 | 0.79 | NOS2 (0.40) | CYP3A4CYP2D6CYP2C9TSHRELANE | |
| SCHEMBL28362259 | 0.79 | KMT2A (0.32) | LMNAALDH1A1CYP3A4MEN1MITF | |
| SCHEMBL28365927 | 0.79 | KMT2A (0.32) | LMNAALDH1A1CYP3A4MEN1MITF | |
| SCHEMBL6805970 | 0.78 | NOS2 (0.33) | HTR2CELANEPRCP | |
| SCHEMBL5792429 | 0.78 | MAPT (0.38) | ALDH1A1MEN1TP53MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912546-A1 | IMPROVED RESERVOIR COMPONENTS | AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997043274-A1 | IMPROVED RESERVOIR COMPONENTS | AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) | 1997-11-20 | — | — | WO | disclosed |