Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.41 |
| ▸ | NPC1 | O15118 | 8/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518281 | 0.85 | HDAC1 (0.39) | ALDH1A1LMNAPOLB | |
| SCHEMBL7397295 | 0.68 | RAB9A (0.39) | RAB9ANPC1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL3266677 | 0.63 | MAPT (0.76) | RAB9ANPC1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL12979794 | 0.63 | MAPT (0.76) | RAB9ANPC1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL6423387 | 0.63 | MAPT (0.76) | RAB9ANPC1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL8518520 | 0.62 | MAPT (0.39) | RAB9ANPC1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL2488962 | 0.62 | MIF (0.74) | RAB9ANPC1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL2488965 | 0.62 | MIF (0.74) | RAB9ANPC1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL6476485 | 0.62 | MIF (0.65) | RAB9ANPC1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL6476482 | 0.62 | MIF (0.65) | RAB9ANPC1KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |