Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394047 | 0.87 | NAMPT (0.49) | KMT2AITGB3ITGA2BDRD2SCN9A | |
| SCHEMBL7397343 | 0.86 | ITGB3 (0.43) | SMN1; SMN2KMT2AITGB3ITGA2BNAMPT | |
| SCHEMBL7400533 | 0.82 | CCKBR (0.49) | ALDH1A1ITGB3ITGA2BSCN9ANAMPT | |
| SCHEMBL8195620 | 0.79 | ITGB3 (0.49) | SMN1; SMN2ITGB3ITGA2BNAMPTCACNA1G | |
| SCHEMBL8518520 | 0.73 | MAPT (0.39) | RAB9ANPC1SMN1; SMN2RECQLMAPT | |
| SCHEMBL7669121 | 0.70 | ITGB3 (0.65) | RAB9ANPC1SMN1; SMN2RECQLMAPT | |
| SCHEMBL7401018 | 0.69 | ITGB3 (0.43) | MAPTKDM4EKMT2AALDH1A1LMNA | |
| SCHEMBL7391455 | 0.68 | ITGB3 (0.42) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL8518521 | 0.68 | RAB9A (0.41) | RAB9ANPC1SMN1; SMN2RECQLMAPT | |
| SCHEMBL7596417 | 0.67 | ITGB3 (0.52) | SMN1; SMN2KMT2AALDH1A1LMNAITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593603-B1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| US-6127359-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-10-03 | — | — | US | disclosed |
| EP-0593603-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-04-27 | — | — | EP | disclosed |
| WO-1993000095-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-07 | — | — | WO | disclosed |