Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | ALKBH1 | Q13686 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28652239 | 0.81 | PDGFRB (0.50) | PDGFRBPDGFRAALKBH1MAOBP4HTM | |
| SCHEMBL30296052 | 0.81 | PDGFRB (0.47) | PDGFRBPDGFRAALKBH1MAOBP4HTM | |
| SCHEMBL7413609 | 0.81 | PDGFRB (0.54) | PDGFRBPDGFRAALKBH1MAOBP4HTM | |
| SCHEMBL7409633 | 0.81 | MAOB (0.50) | PDGFRBPDGFRAALKBH1MAOBP4HTM | |
| SCHEMBL14676863 | 0.81 | PDGFRB (0.50) | PDGFRBPDGFRAALKBH1MAOBP4HTM | |
| SCHEMBL21538106 | 0.80 | MAPT (0.52) | MAOBALOX5SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL25956020 | 0.78 | LTA4H (0.43) | MAOBSMN1; SMN2L3MBTL1LMNARAB9A | |
| SCHEMBL10707032 | 0.77 | P4HTM (0.56) | ALKBH1P4HTMSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL12180347 | 0.77 | DRD2 (0.56) | MAOBALOX5SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL3196407 | 0.75 | ALOX5 (0.53) | MAOBALOX5SMN1; SMN2PRMT5L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869507-A | Azatyrosine analogues | Wang, Hui-Po (TW) | 1999-02-09 | — | — | US | disclosed |
| WO-1999004792-A1 | NOVEL AZATYROSINE ANALOGUES AND PROCESS OF PREPARATION THEREOF | TSAI, HANSEN (TW) | 1999-02-04 | — | — | WO | disclosed |