Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505417 | 0.78 | KDM4E (0.49) | ALDH1A1TSHRRECQLHSD17B10MAPT | |
| SCHEMBL2170909 | 0.78 | IDO1 (0.47) | ALDH1A1IDO1MAPTHTTSIGMAR1 | |
| SCHEMBL8306026 | 0.76 | CA12 (0.57) | CA12CA3CA4CA6CA5A | |
| SCHEMBL7333052 | 0.75 | TAAR1 (0.50) | CA12CA9ALDH1A1IDO1TAAR1 | |
| SCHEMBL8557281 | 0.75 | L3MBTL1 (0.53) | ALDH1A1TSHRHSD17B10IDO1TAAR1 | |
| SCHEMBL1471292 | 0.74 | IDO1 (0.61) | CA12CA3CA4CA6CA5A | |
| SCHEMBL6954997 | 0.74 | MAPT (0.75) | CA12CA3CA4CA6CA5A | |
| SCHEMBL7270407 | 0.74 | CA12 (0.55) | CA12CA3CA4CA6CA5A | |
| SCHEMBL5643983 | 0.74 | CA12 (0.55) | CA12CA3CA4CA6CA5A | |
| SCHEMBL24711106 | 0.74 | CYP2C19 (0.47) | ALDH1A1MAPTHTTKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3738955-A1 | NOVEL 5-HYDROXYTRYPTAMINE RECEPTOR 7 ACTIVITY MODULATORS AND THEIR METHOD OF USE | Temple University Of The Commonwealth System Of Higher Education (US) | 2020-11-18 | — | — | EP | disclosed |
| EP-2970223-B1 | NOVEL 5-HYDROXYTRYPTAMINE RECEPTOR 7 ACTIVITY MODULATORS AND THEIR METHOD OF USE | UNIV TEMPLE (US) | 2020-04-15 | — | — | EP | disclosed |
| EP-0912899-A1 | ENHANCED CHROMATOGRAPHY USING MULTIPHOTON DETECTION | Biotraces, Inc. (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998002750-A1 | ENHANCED CHROMATOGRAPHY USING MULTIPHOTON DETECTION | BIOTRACES, INC. (US) | 1998-01-22 | — | — | WO | disclosed |