SCHEMBL8306026

SCHEMBL8306026

NCCNc1ccccc1N

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.57
CA3 P07451 1/20 0.57
CA4 P22748 1/20 0.57
CA6 P23280 1/20 0.57
CA5A P35218 1/20 0.57
CA7 P43166 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57
CA5B Q9Y2D0 1/20 0.57
ALDH1A1 P00352 2/20 0.55
HSD17B10 Q99714 2/20 0.55
TSHR P16473 1/20 0.55
RECQL P46063 1/20 0.55
IDO1 P14902 2/20 0.48
FERMT2 Q96AC1 1/20 0.46
MAPT P10636 4/20 0.45
KDM4E B2RXH2 2/20 0.45
GAA P10253 2/20 0.45
MEN1 O00255 1/20 0.45
LMNA P02545 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6201094 0.88 MAPT (0.52) CA12CA3CA4CA6CA5A
SCHEMBL9320885 0.87 KAT2B (0.54) CA12CA3CA4CA6CA5A
SCHEMBL215272 0.84 HDAC3 (0.50) ALDH1A1HSD17B10TSHRMAPTKDM4E
SCHEMBL867417 0.84 PRSS1 (0.47) ALDH1A1HSD17B10MAPTKDM4EGAA
SCHEMBL8720375 0.82 HDAC3 (0.53) ALDH1A1HSD17B10TSHRMAPTKDM4E
SCHEMBL6247309 0.82 HDAC3 (0.53) ALDH1A1HSD17B10TSHRMAPTKDM4E
SCHEMBL7375160 0.80 KDM4E (0.49) ALDH1A1HSD17B10TSHRRECQLMAPT
SCHEMBL3628342 0.80 IDO1 (0.47) ALDH1A1HSD17B10RECQLIDO1MAPT
SCHEMBL30128490 0.80 KDM4E (0.49) ALDH1A1HSD17B10TSHRRECQLMAPT
SCHEMBL29922465 0.80 IDO1 (0.47) ALDH1A1HSD17B10RECQLIDO1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4008211-A Betainic azo dyestuffs containing cobalt in complex union with a colorless, tridentate ligand CIBA-GEIGY AG (CH) 1977-02-15 US claimed
CN-114277374-A Etching solution 肇庆微纳芯材料科技有限公司 2022-04-05 CN disclosed
US-10413588-B2 Probiotic function of human intelectin WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2019-09-17 US disclosed
CN-110035739-A Dye composite comprising 12- hydroxy stearic acid, organic amine and dyestuff 欧莱雅 2019-07-19 CN disclosed
CN-109908028-A Cosmetic composition, colouring method and device 莱雅公司 2019-06-21 CN disclosed
CN-104902865-B Without chemical oxidizing agent, the colouring compositions comprising oxidation dye, alkyl sulfate, alkyl poly glucoside, fatty material and nonionic guar gum 莱雅公司 2019-06-11 CN disclosed
CN-108697624-A The oxidising composition for including fatty material and oxygen alkylene surfactant for handling keratin material 莱雅公司 2018-10-23 CN disclosed
US-10082506-B2 Microbial glycans as a target of human intelectin WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2018-09-25 US disclosed
CN-108472235-A The composition for including heterocycle oxidation base and 2- amino -5- ethyl -phenol colour couplers for hair dyeing 莱雅公司 2018-08-31 CN disclosed
CN-108366928-A The composition comprising oxidation base, 2- amino -5- ethyl -phenols colour coupler and fatty material for hair dyeing 莱雅公司 2018-08-03 CN disclosed
CN-1308931-A Keratin fibre oxidation dyeing composition OREAL (FR) 2001-08-22 CN disclosed
CN-1246050-A Oxidizing composition and use thereof for dyeing, permanently setting or bleaching keratin fibres OREAL (FR) 2000-03-01 CN disclosed
CN-1246051-A Oxidizing composition and use thereof for treating keratin fibres OREAL (FR) 2000-03-01 CN disclosed
CN-1244116-A Oxidising composition and use for dyeing, permanently setting or bleaching keratin fibres OREAL (FR) 2000-02-09 CN disclosed
CN-1213961-A Keratin fiber dye compsn. containing pyrazolo-azole compounds, use thereof as dye couplers, and dyeing method OREAL (FR) 1999-04-14 CN disclosed
CN-1042393-C Application of indole derivatives in dyeing of keratose fibre as colour OREAL (FR) 1999-03-10 CN disclosed
CN-1186655-A Oxidation dye composition for keratin fibres, comprising anionic amphiphilic polymer OREAL (FR) 1998-07-08 CN disclosed
CN-1181926-A Oxidation dye composition for keratin fibres, comprising anionic amphiphilic polymer OREAL (FR) 1998-05-20 CN disclosed
CN-1063409-A Indole derivatives is done the application of colour former in the dyeing keratinous fibres process OREAL (FR) 1992-08-12 CN disclosed
US-4008211-A Betainic azo dyestuffs containing cobalt in complex union with a colorless, tridentate ligand CIBA-GEIGY AG (CH) 1977-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10082506-B2 Microbial glycans as a target of human intelectin HINT1, DERL1, ENGASE CA12 2494/4885CA3 4725/4885CA4 3708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.