SCHEMBL8518882

SCHEMBL8518882

CCCCN1CCC(CO)C1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GNAO1 P09471 5/20 0.46
GBA1 P04062 2/20 0.46
GLB1 P16278 1/20 0.46
HTR1A P08908 1/20 0.44
DRD2 P14416 1/20 0.44
DRD1 P21728 1/20 0.44
DRD4 P21917 1/20 0.44
DRD5 P21918 1/20 0.44
DRD3 P35462 1/20 0.44
BCHE P06276 2/20 0.42
GNAI3 P08754 4/20 0.42
GNAI1 P63096 4/20 0.42
ARG1 P05089 1/20 0.42
ARG2 P78540 1/20 0.42
GBA2 Q9HCG7 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9368277 0.94 GNAO1 (0.53) GNAO1GBA1HTR1ADRD2DRD1
Hydrochloric Acid SCHEMBL29518770 0.91 GNAO1 (0.58) GNAO1GBA1HTR1ADRD2DRD1
SCHEMBL2433914 0.89 BCHE (0.49) GBA1GLB1BCHE
SCHEMBL2433913 0.89 BCHE (0.49) GBA1GLB1BCHE
SCHEMBL13560174 0.88 GBA1 (0.43) GNAO1GBA1DRD2DRD1DRD4
SCHEMBL1919292 0.88 GNAO1 (0.53) GNAO1GBA1GLB1GNAI3GNAI1
SCHEMBL19637813 0.88 GBA2 (0.43) GNAO1GBA1GBA2
SCHEMBL9340390 0.87 BCHE (0.44) GBA1GLB1BCHE
SCHEMBL24134595 0.84 HTR1A (0.46) GNAO1GLB1HTR1ADRD2DRD1
SCHEMBL3429374 0.84 ARG1 (0.43) GNAO1GBA1DRD2DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0748310-B1 DIESTERS OF CARBONIC ACID ENDOWED WITH ANTIVIRAL AND ANTI-INFLAMMATORY ACTIVITY ITALFARMACO SPA (IT) 1999-06-02 EP disclosed
US-5827881-A ADMINISTERING FOR TREATMENT OF VIRAL DISEASES OR AS ANTIINFLAMMATORY AGENTS ITALFARMACO S.P.A. (IT) 1998-10-27 US disclosed
EP-0748310-A1 DIESTERS OF CARBONIC ACID ENDOWED WITH ANTIVIRAL AND ANTI-INFLAMMATORY ACTIVITY ITALFARMACO S.p.A. (IT) 1996-12-18 EP disclosed
WO-1995023128-A1 DIESTERS OF CARBONIC ACID ENDOWED WITH ANTIVIRAL AND ANTI-INFLAMMATORY ACTIVITY ITALFARMACO S.P.A. (IT) 1995-08-31 WO disclosed
EP-0600955-A1 5-HT4 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1994-06-15 EP disclosed
WO-1993003725-A1 5-HT4 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1993-03-04 WO disclosed