Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | RIOK2 | Q9BVS4 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CCR4 | P51679 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518945 | 1.00 | MAPT (0.52) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL28134113 | 0.76 | KMT2A (0.61) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL18874941 | 0.76 | KMT2A (0.61) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL8743296 | 0.75 | TDP1 (0.48) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL4908899 | 0.72 | SIGMAR1 (0.50) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL1572609 | 0.72 | TSHR (0.52) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL22062012 | 0.72 | SIGMAR1 (0.50) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL1348095 | 0.72 | TSHR (0.52) | MAPTKMT2AMEN1KDM4ERAB9A | |
| Hydrochloric Acid SCHEMBL5846986 | 0.70 | TSHR (0.50) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL2732741 | 0.69 | MAPT (1.00) | MAPTKMT2AMEN1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6001331-A | INTRODUCING INTO PATIENT BENZYLTHIAZOL-3-IUM DERIVATIVES OF GIVEN FORMULA; ALLOWING TIME FOR COMPOUND TO ASSOCIATE WITH AMYLOID; DETECTING THE LABELED COMPOUND ASSOCIATED WITH AMYLOID DEPOSITS | WARNER-LAMBERT COMPANY (US) | 1999-12-14 | — | — | US | disclosed |
| WO-1997026919-A2 | METHOD OF IMAGING AMYLOID DEPOSITS | WARNER-LAMBERT COMPANY (US) | 1997-07-31 | — | — | WO | disclosed |