SCHEMBL8519208

SCHEMBL8519208

NCCNCCNC(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA5B Q9Y2D0 6/20 0.55
CA12 O43570 5/20 0.55
CA6 P23280 5/20 0.55
CA7 P43166 5/20 0.55
CA9 Q16790 5/20 0.55
CA14 Q9ULX7 5/20 0.55
CA5A P35218 5/20 0.55
CA3 P07451 4/20 0.55
CA2 P00918 4/20 0.55
CA4 P22748 4/20 0.55
ALOX15 P16050 3/20 0.55
LMNA P02545 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
CA1 P00915 2/20 0.55
ALDH1A1 P00352 1/20 0.55
TP53 P04637 1/20 0.55
KDM4E B2RXH2 1/20 0.52
MEN1 O00255 2/20 0.50
RECQL P46063 2/20 0.50
KMT2A Q03164 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8519355 1.00 CA5B (0.55) CA5BCA12CA6CA7CA9
SCHEMBL13756331 0.91 CASP2 (0.59) CA5BCA12CA6CA7CA9
SCHEMBL2240590 0.87 CA3 (0.42) CA5BCA12CA6CA7CA9
SCHEMBL322077 0.84
Trientine SCHEMBL20639324 0.84 CA12 (0.69) CA5BCA12CA6CA7CA9
Bicarbonate SCHEMBL10634656 0.84 CA12 (0.69) CA5BCA12CA6CA7CA9
Trientine SCHEMBL505672 0.82 LMNA (0.58) CA5BCA12CA6CA7CA9
SCHEMBL4412170 0.82 CA5B (0.58) CA5BCA12CA6CA7CA9
Succinic Acid SCHEMBL2447637 0.82 LMNA (0.58) CA5BCA12CA6CA7CA9
SCHEMBL27353046 0.82 CA5B (0.58) CA5BCA12CA6CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110628402-B Cross-linking agent and organogel water shutoff agent, and preparation method and application thereof 中国石油化工股份有限公司 2022-03-01 CN claimed
CN-110628402-A Cross-linking agent and organogel water shutoff agent, and preparation method and application thereof 中国石油化工股份有限公司 2019-12-31 CN claimed
CN-103396776-B A kind of oil and water well self-generating foam unblocking agent and de-plugging process XIAN PETROLEUM UNIV. (CN) 2016-01-06 CN claimed
CN-103396776-A Self-generating foam blocking removal agent for oil-water well and blocking removal process UNIV XI AN SHIYOU 2013-11-20 CN claimed
CN-114705804-B Device and method for continuously measuring soluble carbon in soil or aqueous solution 安徽师范大学 2024-08-23 CN disclosed
US-11998584-B2 Conjugate of a tubulysin analog with branched linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2024-06-04 US disclosed
US-11873281-B2 Conjugates of cell binding molecules with cytotoxic agents HANGZHOU DAC BIOTECH CO., LTD. (CN) 2024-01-16 US disclosed
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 US disclosed
US-20230165930-A1 CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-06-01 US disclosed
US-20230165931-A1 A CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-06-01 US disclosed
US-20230149502-A1 CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-05-18 US disclosed
CN-115738600-A Amino functional ion compound anhydrous absorbent for absorbing carbon dioxide and preparation method thereof 安徽工业大学 2023-03-07 CN disclosed
EP-2678349-A1 C-4\" POSITION SUBSTITUTED MACROLIDE DERIVATIVE Taisho Pharmaceutical Co., Ltd. (JP) 2014-01-01 EP disclosed
CN-103396776-A Self-generating foam blocking removal agent for oil-water well and blocking removal process UNIV XI AN SHIYOU 2013-11-20 CN disclosed
WO-2012115256-A1 C-4\" POSITION SUBSTITUTED MACROLIDE DERIVATIVE TAISHO PHARMACEUTICAL CO., LTD. (JP) 2012-08-30 WO disclosed
WO-2011147033-A2 COMPOSITIONS AND METHODS FOR CAPTURING CARBON DIOXIDE SAINT MARY'S UNIVERSITY (CA) 2011-12-01 WO disclosed
CN-101537300-B Recyclable sulfur dioxide gas absorbent and preparation method thereof UNIV HEFEI TECHNOLOGY 2011-08-10 CN disclosed
CN-101537300-A Recyclable sulfur dioxide gas absorbent and preparation method thereof UNIV HEFEI TECHNOLOGY 2009-09-23 CN disclosed
US-5972038-A METAL PHTHALOCYANINE PHOTOBLEACH COMPOUND; DIETHYLENE TRIAMINE PENTAACETATE, DIETHYLENE TRIAMINE PENTA(METHYLENE PHOSPHONATE), AND MIXTURES THEREOF. THE PROCTER & GAMBLE COMPANY (US) 1999-10-26 US disclosed
WO-1997031994-A1 CHELANT ENHANCED PHOTOBLEACHING THE PROCTER & GAMBLE COMPANY (US) 1997-09-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS GIPR, GLP1R, GCGR CA5B 2330/4885CA12 2875/4885CA6 2445/4885
US-20230165930-A1 CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS TEKT1, CD2BP2, TEK CA5B 2164/4885CA12 1484/4885CA6 2275/4885
US-20230165931-A1 A CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS TEKT1, CD2BP2, CD4 CA5B 2246/4885CA12 1484/4885CA6 2407/4885
US-11873281-B2 Conjugates of cell binding molecules with cytotoxic agents CD4, CD2, CD47 CA5B 2799/4885CA12 952/4885CA6 3056/4885
US-11998584-B2 Conjugate of a tubulysin analog with branched linkers TEKT1, TEK, CD2BP2 CA5B 1939/4885CA12 1235/4885CA6 2077/4885
US-20230149502-A1 CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS TEKT1, CD2BP2, TEK CA5B 2164/4885CA12 1484/4885CA6 2275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.