Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8519811 | 0.92 | ABCB11 (0.48) | ABCB11PTGS2LMNAALDH1A1CYP1A2 | |
| SCHEMBL8519641 | 0.89 | PTGS2 (0.53) | ABCB11PTGS2LMNAALDH1A1CYP1A2 | |
| SCHEMBL8518493 | 0.86 | ABCB11 (0.60) | ABCB11PTGS2LMNAALDH1A1CYP1A2 | |
| SCHEMBL8518610 | 0.83 | NAMPT (0.44) | ABCB11PTGS2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8518458 | 0.83 | PTGS2 (0.55) | ABCB11PTGS2LMNAALDH1A1CYP1A2 | |
| SCHEMBL8519110 | 0.78 | ABCB11 (0.64) | ABCB11PTGS2LMNAALDH1A1CYP1A2 | |
| SCHEMBL8519533 | 0.78 | ABCB11 (0.57) | ABCB11PTGS2LMNAALDH1A1CYP1A2 | |
| SCHEMBL8518402 | 0.77 | ABCB11 (0.47) | ABCB11PTGS2LMNAALDH1A1CYP1A2 | |
| SCHEMBL8519895 | 0.77 | ABCB11 (0.51) | ABCB11PTGS2LMNAALDH1A1CYP1A2 | |
| SCHEMBL8518393 | 0.77 | PTGS2 (0.47) | ABCB11PTGS2LMNAALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952368-A | AN INHIBITORS OF PROSTAGLANDIN G/H SYNTHASE, ANTIINFLAMMATORY AND ANALGESIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1999-09-14 | — | — | US | disclosed |