Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518393 | 0.94 | PTGS2 (0.47) | ABCB11PTGS2LMNAALDH1A1CYP1A2 | |
| SCHEMBL8519370 | 0.92 | ABCB11 (0.46) | ABCB11PTGS2LMNAALDH1A1CYP1A2 | |
| SCHEMBL8518493 | 0.92 | ABCB11 (0.60) | ABCB11PTGS2LMNAALDH1A1CYP1A2 | |
| SCHEMBL8519156 | 0.90 | OPRK1 (0.46) | ABCB11PTGS2LMNAALDH1A1CYP1A2 | |
| SCHEMBL8519798 | 0.90 | ABCB11 (0.43) | ABCB11PTGS2LMNAALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL8518624 | 0.89 | VNN1 (0.43) | ABCB11PTGS2CYP1A2TSHRHPGD | |
| SCHEMBL8519559 | 0.88 | ABCB11 (0.38) | ABCB11PTGS2ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8519019 | 0.85 | SMN1; SMN2 (0.41) | ABCB11PTGS2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8520241 | 0.85 | KMT2A (0.38) | ABCB11PTGS2LMNAALDH1A1CYP1A2 | |
| SCHEMBL8519811 | 0.84 | ABCB11 (0.48) | ABCB11PTGS2LMNAALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952368-A | AN INHIBITORS OF PROSTAGLANDIN G/H SYNTHASE, ANTIINFLAMMATORY AND ANALGESIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1999-09-14 | — | — | US | disclosed |