Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8519131 | 0.99 | ABCB11 (0.50) | ABCB11PTGS2LMNASMN1; SMN2TSHR | |
| SCHEMBL8519780 | 0.91 | LMNA (0.41) | ABCB11PTGS2LMNASMN1; SMN2TSHR | |
| SCHEMBL8518478 | 0.91 | MEN1 (0.43) | ABCB11PTGS2TSHRALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL8518624 | 0.90 | VNN1 (0.43) | ABCB11PTGS2TSHRCYP1A2HTT | |
| SCHEMBL8519457 | 0.89 | GAA (0.48) | SMN1; SMN2TSHRALDH1A1HTTNAMPT | |
| SCHEMBL8518493 | 0.88 | ABCB11 (0.60) | ABCB11PTGS2LMNASMN1; SMN2TSHR | |
| SCHEMBL8519641 | 0.87 | PTGS2 (0.53) | ABCB11PTGS2LMNASMN1; SMN2TSHR | |
| SCHEMBL8518356 | 0.84 | ABCB11 (0.54) | ABCB11PTGS2LMNASMN1; SMN2TSHR | |
| SCHEMBL8518342 | 0.82 | TSHR (0.43) | LMNASMN1; SMN2TSHRALDH1A1HTT | |
| SCHEMBL8518402 | 0.81 | ABCB11 (0.47) | ABCB11PTGS2LMNASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952368-A | AN INHIBITORS OF PROSTAGLANDIN G/H SYNTHASE, ANTIINFLAMMATORY AND ANALGESIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1999-09-14 | — | — | US | disclosed |