Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518555 | 0.83 | CNR1 (0.42) | TAAR1LPLLIPGALDH1A1CA2 | |
| SCHEMBL13071242 | 0.75 | TRPA1 (0.44) | CYP2A6TRPA1CYP1A2PARP1TP53 | |
| SCHEMBL11576986 | 0.75 | — | — | |
| SCHEMBL14615927 | 0.71 | TRPA1 (0.41) | CYP2A6TRPA1CYP1A2PARP1TP53 | |
| SCHEMBL19766178 | 0.70 | AHR (0.48) | CYP2A6TRPA1CYP1A2PARP1TP53 | |
| SCHEMBL8519607 | 0.70 | PARP1 (0.42) | CYP2A6TRPA1CYP1A2PARP1TAAR1 | |
| SCHEMBL92784 | 0.70 | TAAR1 (0.60) | CYP1A2TAAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL92786 | 0.70 | MEN1 (0.53) | PARP1TAAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL36295 | 0.69 | TP53 (0.67) | CYP2A6TRPA1CYP1A2TP53TAAR1 | |
| SCHEMBL9588776 | 0.68 | ALOX15 (0.53) | CYP2A6TRPA1CYP1A2PARP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679662-B1 | Catalyst component for the polymerization of olefins | NIPPON OIL CO LTD (JP) | 1999-07-14 | — | — | EP | disclosed |
| US-5728641-A | Catalyst component for the polymerization of olefins | NIPPON OIL COMPANY, LIMITED (JP) | 1998-03-17 | — | — | US | disclosed |
| EP-0679662-A1 | Catalyst component for the polymerization of olefins | NIPPON OIL CO. LTD. (JP) | 1995-11-02 | — | — | EP | disclosed |