Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10509298 | 0.85 | TRPV1 (0.46) | ALDH1A1KMT2ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL7431314 | 0.85 | HPGD (0.41) | ALDH1A1KMT2ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL5807162 | 0.85 | HPGD (0.52) | ALDH1A1NPC1RAB9ALMNAMAPT | |
| SCHEMBL5057819 | 0.85 | HPGD (0.52) | ALDH1A1NPC1RAB9ALMNAMAPT | |
| SCHEMBL7435235 | 0.82 | ALDH1A1 (0.54) | ALDH1A1RAB9AKMT2AHPGD | |
| SCHEMBL11412947 | 0.78 | HDAC2 (0.46) | ALDH1A1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL7717557 | 0.74 | TSHR (0.51) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8770332 | 0.73 | TSHR (0.53) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5812287 | 0.73 | MAPT (0.42) | ALDH1A1NPC1RAB9AKMT2ALMNA | |
| SCHEMBL22570415 | 0.71 | HDAC1 (0.66) | ALDH1A1NPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115163-A1 | MARKED PEPTIDES AND USE THEREOF FOR ASSAYING CIRCULATING IRAP | VRIJE UNIVERSITEIT BRUSSEL (BE) | 2012-05-10 | — | — | US | disclosed |
| EP-2432800-A2 | MARKED PEPTIDES AND USE THEREOF FOR ASSAYING CIRCULATING IRAP | Université Joseph Fourier (FR) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133806-A2 | MARKED PEPTIDES AND USE THEREOF FOR ASSAYING CIRCULATING IRAP | UNIVERSITE JOSEPH FOURIER (FR) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115163-A1 | MARKED PEPTIDES AND USE THEREOF FOR ASSAYING CIRCULATING IRAP | IAPP, ANPEP, ENPEP | ALDH1A1 4041/4885NPC1 3219/4885RAB9A 1876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.