Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL117727 | 0.81 | CACNB4 (0.40) | DAOALDH1A1CA1CA2CA12 | |
| SCHEMBL116597 | 0.81 | ALDH1A1 (0.37) | DDB1CRBNALDH1A1MEN1KMT2A | |
| SCHEMBL10710508 | 0.81 | DDB1 (0.37) | DAODDB1CRBNALDH1A1CA1 | |
| SCHEMBL11094086 | 0.80 | HTR1A (0.34) | ALDH1A1MEN1KMT2AGAAHTR2C | |
| SCHEMBL1321330 | 0.79 | HTR2C (0.46) | DDB1CRBNALDH1A1MEN1KMT2A | |
| SCHEMBL10714048 | 0.78 | ALDH1A1 (0.36) | DAOALDH1A1KMT2ACA1CA2 | |
| SCHEMBL10711888 | 0.78 | BRD4 (0.40) | ALDH1A1CREBBPGSK3BMAPTHTR2B | |
| SCHEMBL24112725 | 0.77 | ALDH1A1 (0.43) | DAODDB1CRBNALDH1A1MEN1 | |
| SCHEMBL24112230 | 0.77 | ALDH1A1 (0.43) | DAODDB1CRBNALDH1A1MEN1 | |
| SCHEMBL10714343 | 0.77 | LMNA (0.41) | DDB1CRBNALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4252723-A | Air oxidation of oxindoles to isatins | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1981-02-24 | — | — | US | disclosed |
| US-4188325-A | Isatin process and products | REGENTS OF UNIVERSITY OF MINNESOTA (US) | 1980-02-12 | — | — | US | disclosed |
| US-4186132-A | Isatin products | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1980-01-29 | — | — | US | disclosed |
| US-RE29882-E | SALT FORMATION, REARRANGEMENT, DESULFURIZATION | OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1979-01-16 | — | — | US | disclosed |
| US-4056569-A | Ortho-[(alkylthio)(aminocarbonyl)methyl]anilines | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1977-11-01 | — | — | US | disclosed |
| US-3996264-A | Synthesis of oxindoles from anilines and intermediates therein | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1976-12-07 | — | — | US | disclosed |
| US-3972894-A | Synthesis of oxindoles from anilines and β-thio carboxylic esters or amides | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1976-08-03 | — | — | US | disclosed |
| US-3960926-A | Process for preparing azasulfonium halide salts | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1976-06-01 | — | — | US | disclosed |
| US-3954797-A | Process for preparing azasulfonium halide salts | CHROMALLOY AMERICAN CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |