Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | MGLL | Q99685 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21389415 | 0.88 | SMN1; SMN2 (0.31) | ALDH1A1SMN1; SMN2CYP19A1MEN1RAB9A | |
| SCHEMBL24796036 | 0.77 | ALDH1A1 (0.31) | ALDH1A1MEN1RAB9AKMT2A | |
| SCHEMBL21389465 | 0.77 | ALDH1A1 (0.31) | ALDH1A1MEN1RAB9AKMT2A | |
| SCHEMBL21389463 | 0.77 | ALDH1A1 (0.31) | ALDH1A1MEN1RAB9AKMT2A | |
| SCHEMBL6551354 | 0.72 | MMP8 (0.37) | FAAHALDH1A1CYP19A1MAPT | |
| SCHEMBL21389322 | 0.72 | KDM4E (0.32) | ALDH1A1 | |
| SCHEMBL21389504 | 0.72 | KDM4E (0.32) | ALDH1A1 | |
| SCHEMBL24796420 | 0.72 | KDM4E (0.32) | ALDH1A1 | |
| SCHEMBL22518781 | 0.67 | EHMT2 (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL22493942 | 0.67 | EHMT2 (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722437-B1 | CYCLOALKANEDIOLS AND THEIR USE IN PREPARING CHIRAL COMPOUNDS | CHIROTECH TECHNOLOGY LTD (GB) | 1999-08-25 | — | — | EP | disclosed |
| EP-0722437-A1 | CYCLOALKANEDIOLS AND THEIR USE IN PREPARING CHIRAL COMPOUNDS | Chiroscience Limited (GB) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995009839-A1 | CYCLOALKANEDIOLS AND THEIR USE IN PREPARING CHIRAL COMPOUNDS | CHIROSCIENCE LIMITED (GB) | 1995-04-13 | — | — | WO | disclosed |