Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | BRD2 | P25440 | 3/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7828642 | 0.75 | HDAC3 (0.51) | RAB9AL3MBTL1SMN1; SMN2BRD4BRD2 | |
| SCHEMBL8542158 | 0.71 | CYP3A4 (0.39) | SMN1; SMN2BRD4BRD2BRD3CYP3A4 | |
| SCHEMBL5638173 | 0.70 | MEN1 (0.60) | RAB9ANPC1L3MBTL1SMN1; SMN2CASP3 | |
| SCHEMBL8553126 | 0.70 | MEN1 (0.42) | RAB9ANPC1SMN1; SMN2POLBNPSR1 | |
| SCHEMBL8547679 | 0.69 | GRIN2B (0.38) | L3MBTL1BRD4BRD2BRD3CYP3A4 | |
| SCHEMBL876242 | 0.68 | CASP1 (0.48) | RAB9ANPC1SMN1; SMN2POLBCASP1 | |
| Carbamic Acid SCHEMBL29087081 | 0.67 | MEN1 (0.56) | RAB9ANPC1L3MBTL1SMN1; SMN2CASP3 | |
| SCHEMBL7543329 | 0.65 | SENP1 (0.51) | RAB9ANPC1BRD4BRD2BRD3 | |
| SCHEMBL7544354 | 0.65 | SENP1 (0.51) | RAB9ANPC1BRD4BRD2BRD3 | |
| SCHEMBL7544783 | 0.65 | SCN9A (0.51) | RAB9ANPC1BRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934282-A1 | 1,4-BENZODIAZEPINONES AND THEIR USES AS CCK ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015535-A1 | 1,4-BENZODIAZEPINONES AND THEIR USES AS CCK ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-16 | — | — | WO | disclosed |