Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7828642 | 0.79 | HDAC3 (0.51) | NPSR1ALDH1A1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL8542158 | 0.74 | CYP3A4 (0.39) | KMT2AALDH1A1SMN1; SMN2MAPTSENP1 | |
| SCHEMBL8547679 | 0.73 | GRIN2B (0.38) | ALDH1A1SENP1POLBCTRB1 | |
| SCHEMBL8558106 | 0.73 | SENP1 (0.49) | ALDH1A1SENP1 | |
| SCHEMBL7423680 | 0.70 | L3MBTL1 (0.52) | ALDH1A1NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL8553128 | 0.70 | CBLB (0.56) | — | |
| SCHEMBL8520160 | 0.70 | RAB9A (0.42) | NPSR1NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL13156074 | 0.70 | MAPT (0.50) | MEN1KMT2ANPSR1F10PRKDC | |
| SCHEMBL15201849 | 0.68 | F10 (0.56) | MEN1KMT2ANPSR1LIPEF10 | |
| SCHEMBL5638173 | 0.68 | MEN1 (0.60) | MEN1KMT2ANPSR1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672037-B1 | 1,4-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS CCK-MODULATORS | GLAXO GROUP LTD (GB) | 1998-07-08 | — | — | EP | disclosed |
| US-5569654-A | ADMINISTERING AS ANTAGONISTS OF GASTRIN AND CHOLECYSTOKININ | GLAXO GROUP LIMITED (GB) | 1996-10-29 | — | — | US | disclosed |