SCHEMBL8520314

SCHEMBL8520314

CCCC(CC[C@@H](O)C/C=C\CCCCCCC1(C(=O)O)CCO1)CC(O)CO

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.41
FFAR4 Q5NUL3 1/20 0.41
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
FAAH O00519 4/20 0.37
SPTLC1 O15269 1/20 0.35
SPTLC2 O15270 1/20 0.35
DGKA P23743 1/20 0.33
ALDH1A1 P00352 1/20 0.30
LTB4R Q15722 1/20 0.30
LTB4R2 Q9NPC1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1323910 0.92 FFAR1 (0.36) FFAR1FFAR4FAAHSPTLC1SPTLC2
SCHEMBL1325116 0.85 LMNA (0.32) FFAR1FFAR4
SCHEMBL10974057 0.83 FFAR1 (0.60) FFAR1FFAR4NFKB1NFKB2RELA
SCHEMBL8667713 0.81 LMNA (0.38) FFAR1FFAR4
SCHEMBL8520442 0.81 LMNA (0.38) FFAR1FFAR4
SCHEMBL5342603 0.76 TERT (0.47) FAAH
SCHEMBL8469411 0.76 LMNA (0.38) FFAR1FFAR4
SCHEMBL16500275 0.75 FFAR1 (0.52) FFAR1FFAR4NFKB1NFKB2RELA
SCHEMBL8685383 0.72 DGKA (0.53) FFAR1FFAR4FAAHDGKA
SCHEMBL8519329 0.71 ACACB (0.34) FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0633019-B1 Pressurized gas packagings using polyoxyethylene glyceryl fatty acid esters as suspension stabilizers and valve lubricants ASTA MEDICA AG (DE) 1999-08-11 EP claimed