Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 17/20 | 0.74 |
| ▸ | ICMT | O60725 | 1/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8519014 | 0.84 | CASP1 (0.75) | CASP1ICMT | |
| SCHEMBL5682936 | 0.83 | CASP1 (0.73) | CASP1 | |
| SCHEMBL8520343 | 0.79 | CASP1 (0.65) | CASP1ICMT | |
| SCHEMBL5615819 | 0.73 | CASP1 (0.62) | CASP1ICMTITGAV | |
| SCHEMBL5615814 | 0.73 | CASP1 (0.62) | CASP1ICMTITGAV | |
| SCHEMBL5682833 | 0.71 | CASP1 (0.74) | CASP1 | |
| SCHEMBL5679376 | 0.70 | CASP1 (0.72) | CASP1 | |
| SCHEMBL12994829 | 0.69 | CASP1 (0.60) | CASP1ICMT | |
| SCHEMBL5680766 | 0.69 | MMP2 (0.56) | — | |
| SCHEMBL7427061 | 0.68 | CASP1 (0.57) | CASP1ICMTITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0932600-A2 | SULFONAMIDE SUBSTITUTED ASPARTIC ACID INTERLEUKIN-1$g(b) CONVERTING ENZYME INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-08-04 | — | — | EP | disclosed |
| WO-1998016504-A2 | SULFONAMIDE SUBSTITUTED ASPARTIC ACID INTERLEUKIN-1β CONVERTING ENZYME INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1998-04-23 | — | — | WO | disclosed |