Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 14/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8519018 | 0.83 | CASP1 (0.68) | CASP1 | |
| SCHEMBL5682936 | 0.81 | CASP1 (0.73) | CASP1 | |
| SCHEMBL8520340 | 0.79 | CASP1 (0.74) | CASP1ICMT | |
| SCHEMBL7744231 | 0.77 | CASP1 (0.51) | CASP1L3MBTL1ICMT | |
| SCHEMBL12994829 | 0.71 | CASP1 (0.60) | CASP1ICMT | |
| SCHEMBL6279917 | 0.70 | SLC1A3 (0.50) | CASP1TDP1L3MBTL1 | |
| SCHEMBL5682833 | 0.68 | CASP1 (0.74) | CASP1 | |
| SCHEMBL5679376 | 0.67 | CASP1 (0.72) | CASP1 | |
| SCHEMBL11141447 | 0.67 | PTGS1 (0.65) | PTGS1FFAR1 | |
| SCHEMBL13255684 | 0.67 | CASP1 (0.46) | CASP1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0932600-A2 | SULFONAMIDE SUBSTITUTED ASPARTIC ACID INTERLEUKIN-1$g(b) CONVERTING ENZYME INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-08-04 | — | — | EP | disclosed |
| WO-1998016504-A2 | SULFONAMIDE SUBSTITUTED ASPARTIC ACID INTERLEUKIN-1β CONVERTING ENZYME INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1998-04-23 | — | — | WO | disclosed |