Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520342 | 0.85 | ALDH1A1 (0.38) | THRBALDH1A1TSHR | |
| SCHEMBL6906556 | 0.81 | THRB (0.33) | THRBALDH1A1TSHR | |
| SCHEMBL27943024 | 0.80 | TSHR (0.45) | TSHR | |
| SCHEMBL751393 | 0.80 | TSHR (0.45) | TSHR | |
| SCHEMBL27777481 | 0.79 | TSHR (0.36) | THRBALDH1A1TSHR | |
| SCHEMBL1536959 | 0.78 | ALDH1A1 (0.38) | THRBALDH1A1TSHR | |
| SCHEMBL751394 | 0.78 | ALDH1A1 (0.38) | THRBALDH1A1TSHR | |
| SCHEMBL1537086 | 0.78 | ALDH1A1 (0.38) | THRBALDH1A1TSHR | |
| SCHEMBL5084731 | 0.78 | ALDH1A1 (0.38) | THRBALDH1A1TSHR | |
| SCHEMBL1536846 | 0.78 | ALDH1A1 (0.38) | THRBALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1510533-B1 | Block copolymer comprising a vinylactam block, cosmetic composition and use of this polymer in cosmetics | OREAL (FR) | 2006-12-06 | — | — | EP | claimed |
| US-20060088487-A1 | Block ethylenic copolymers comprising a vinyllactam block, cosmetic or pharmaceutical compositions containing them and cosmetic use of these copolymers | L'OREAL S.A. (FR) | 2006-04-27 | — | — | US | claimed |
| US-20050238594-A1 | Block ethylenic copolymers comprising a vinyllactam block, cosmetic or pharmaceutical compositions comprising them and cosmetic use of these copolymers | L'OREAL S.A. (FR) | 2005-10-27 | — | — | US | claimed |
| US-20120027698-A9 | COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE COPOLYMER COMPRISING AT LEAST ONE IONIZABLE GROUP, AND COSMETIC TREATMENT PROCESS | L'OREAL S.A. | 2012-02-02 | — | — | US | disclosed |
| US-20100278764-A1 | COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE COPOLYMER COMPRISING AT LEAST ONE IONIZABLE GROUP, AND COSMETIC TREATMENT PROCESS | L'OREAL S.A. | 2010-11-04 | — | — | US | disclosed |
| US-20100040572-A1 | BLOCK ETHYLENIC COPOLYMERS COMPRISING A VINYLLACTAM BLOCK, COSMETIC COMPOSITIONS CONTAINING THEM AND COSMETIC USE OF THESE COPOLYMERS | L'OREAL, S.A. (FR) | 2010-02-18 | — | — | US | disclosed |
| US-20070264208-A1 | Cosmetic and/or pharmaceutical composition comprising at least one copolymer comprising at least one ionizable group, and cosmetic treatment process | L'OREAL S.A. (FR) | 2007-11-15 | — | — | US | disclosed |
| US-20060088487-A1 | Block ethylenic copolymers comprising a vinyllactam block, cosmetic or pharmaceutical compositions containing them and cosmetic use of these copolymers | L'OREAL S.A. (FR) | 2006-04-27 | — | — | US | disclosed |
| US-20050238594-A1 | Block ethylenic copolymers comprising a vinyllactam block, cosmetic or pharmaceutical compositions comprising them and cosmetic use of these copolymers | L'OREAL S.A. (FR) | 2005-10-27 | — | — | US | disclosed |
| US-20050101740-A1 | Block ethylenic copolymers comprising a vinyllactam block, cosmetic compositions containing them and cosmetic use of these copolymers | L'OREAL S.A. (FR) | 2005-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050238594-A1 | Block ethylenic copolymers comprising a vinyllactam block, cosmetic or pharmaceutical compositions comprising them and cosmetic use of these copolymers | KRT18, DSG1, VCL | THRB 1233/4885ALDH1A1 2416/4885TSHR 3721/4885 |
| US-20060088487-A1 | Block ethylenic copolymers comprising a vinyllactam block, cosmetic or pharmaceutical compositions containing them and cosmetic use of these copolymers | KRT18, CUTA, SCNN1B | THRB 586/4885ALDH1A1 855/4885TSHR 4122/4885 |
| US-20070264208-A1 | Cosmetic and/or pharmaceutical composition comprising at least one copolymer comprising at least one ionizable group, and cosmetic treatment process | KRT18, DSG1, DSC1 | THRB 4201/4885ALDH1A1 1821/4885TSHR 3978/4885 |
| US-20120027698-A9 | COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE COPOLYMER COMPRISING AT LEAST ONE IONIZABLE GROUP, AND COSMETIC TREATMENT PROCESS | KRT18, DSG1, DSC1 | THRB 4070/4885ALDH1A1 1508/4885TSHR 3847/4885 |
| US-20100278764-A1 | COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE COPOLYMER COMPRISING AT LEAST ONE IONIZABLE GROUP, AND COSMETIC TREATMENT PROCESS | KRT18, DSG1, DSC1 | THRB 4070/4885ALDH1A1 1508/4885TSHR 3847/4885 |
| US-20100040572-A1 | BLOCK ETHYLENIC COPOLYMERS COMPRISING A VINYLLACTAM BLOCK, COSMETIC COMPOSITIONS CONTAINING THEM AND COSMETIC USE OF THESE COPOLYMERS | GLA, ERCC1, PGM2 | THRB 613/4885ALDH1A1 906/4885TSHR 2844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.