Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PTPRA | P18433 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11809220 | 0.77 | SLC1A5 (0.47) | NPC1RAB9ASMN1; SMN2SLC1A5KDM4E | |
| SCHEMBL8186213 | 0.75 | CYP4A11 (0.51) | NPC1GABRA5TSHRPSMB5ALDH1A1 | |
| SCHEMBL30222272 | 0.73 | PTGS2 (0.46) | SMN1; SMN2ALDH1A1KDM4EHTTCYP3A4 | |
| SCHEMBL5983552 | 0.73 | PTGS2 (0.46) | SMN1; SMN2ALDH1A1KDM4EHTTCYP3A4 | |
| SCHEMBL5112475 | 0.73 | PTGS2 (0.46) | SMN1; SMN2ALDH1A1KDM4EHTTCYP3A4 | |
| SCHEMBL13562903 | 0.72 | ALDH1A1 (0.47) | NPC1RAB9ASMN1; SMN2GABRA5TSHR | |
| SCHEMBL7822153 | 0.72 | PTGS2 (0.44) | SMN1; SMN2CD274TSHRALDH1A1CYP2C19 | |
| SCHEMBL1063487 | 0.72 | PTGS2 (0.44) | SMN1; SMN2ALDH1A1KDM4ECYP3A4PTGS1 | |
| SCHEMBL7784447 | 0.71 | TDP1 (0.44) | NPC1RAB9ASMN1; SMN2GABRA5TSHR | |
| SCHEMBL8724339 | 0.71 | GABRA5 (0.40) | NPC1RAB9ASMN1; SMN2SLC1A5GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854866-B1 | PROCESS FOR THE PREPARATION OF 2-(PYRID-2-YLOXYMETHYL)PHENYLACETATES AS PESTICIDE INTERMEDIATES | ZENECA LTD (GB) | 1999-11-17 | — | — | EP | claimed |