SCHEMBL8520583

SCHEMBL8520583

C=C(C)c1ccccc1.C=Cc1ccc(C(C)(C)C)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESRRG P62508 2/20 0.47
ALDH1A1 P00352 2/20 0.42
TSHR P16473 2/20 0.42
MAPT P10636 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
TRPV1 Q8NER1 1/20 0.40
KCNK9 Q9NPC2 1/20 0.39
CYP1A2 P05177 1/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
MEN1 O00255 1/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
TNF P01375 1/20 0.37
KLF5 Q13887 1/20 0.37
NOD1 Q9Y239 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9017221 0.86 L3MBTL1 (0.49) ESRRGALDH1A1TSHRMAPTL3MBTL1
Styrene SCHEMBL7512832 0.84 ALDH1A1 (0.61) ESRRGALDH1A1TSHRMAPTL3MBTL1
Styrene SCHEMBL315930 0.84 ALDH1A1 (0.61) ALDH1A1TSHRMAPTTDP1NPC1
SCHEMBL472890 0.82 ALDH1A1 (0.48) ALDH1A1TSHRMAPTTDP1NPC1
Phenol SCHEMBL7603296 0.81 LMNA (0.54) ESRRGALDH1A1TSHRMAPTL3MBTL1
Styrene SCHEMBL2941460 0.80 ALDH1A1 (0.56) ALDH1A1TSHRMAPTTDP1NPC1
SCHEMBL3109133 0.80 ALDH1A1 (0.47) ESRRGALDH1A1TSHRMAPTL3MBTL1
Benzene SCHEMBL8586542 0.80 ALDH1A1 (0.48) ESRRGALDH1A1TSHRMAPTTRPV1
SCHEMBL15198 0.80 ALDH1A1 (0.58) ALDH1A1TSHRMAPTTDP1TRPV1
SCHEMBL7603044 0.80 ESRRG (0.41) ESRRGALDH1A1TSHRMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0951496-A2 ALKYD AND ARALKYD DERIVATIVES OF PHENOLIC POLYMERS GEORGIA-PACIFIC RESINS, INC. (US) 1999-10-27 EP claimed
WO-1998030596-A2 ALKYD AND ARALKYD DERIVATIVES OF PHENOLIC POLYMERS GEORGIA-PACIFIC RESINS, INC. (US) 1998-07-16 WO claimed
CN-110352212-A Acrylic resin biaxially-stretched film and its manufacturing method 株式会社可乐丽 2019-10-18 CN disclosed
CN-109562553-A The manufacturing method and extruded resin sheet of extruded resin sheet 株式会社可乐丽 2019-04-02 CN disclosed
CN-106715078-B The manufacturing method and extruded resin sheet of extruded resin sheet 株式会社可乐丽 2019-01-04 CN disclosed
CN-108778675-A Method for producing extruded resin sheet and extruded resin sheet 株式会社可乐丽 2018-11-09 CN disclosed
CN-107849327-A Resin combination, products formed and layered product 株式会社可乐丽 2018-03-27 CN disclosed
CN-107250261-A Resin combination, products formed and layered product 株式会社可乐丽 2017-10-13 CN disclosed