Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL8173379 | 0.86 | HPGD (0.46) | SMN1; SMN2HPGDALDH1A1ABCB1CYP3A4 | |
| Benzoyl Chloride SCHEMBL8173467 | 0.86 | HPGD (0.46) | SMN1; SMN2HPGDALDH1A1ABCB1CYP3A4 | |
| Hydrochloric Acid SCHEMBL8166435 | 0.86 | HPGD (0.46) | SMN1; SMN2HPGDALDH1A1ABCB1CYP3A4 | |
| SCHEMBL7478788 | 0.86 | LOXL2 (0.49) | SMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL8006902 | 0.84 | LOXL2 (0.47) | SMN1; SMN2HPGDMAPT | |
| SCHEMBL9247156 | 0.79 | SRD5A2 (0.50) | SMN1; SMN2HPGDALDH1A1MAPTTDP1 | |
| SCHEMBL9507319 | 0.79 | ALDH1A1 (0.52) | SMN1; SMN2HPGDALDH1A1MAPTHTT | |
| SCHEMBL9203545 | 0.79 | ESR1 (0.48) | SMN1; SMN2HPGDCYP3A4MAPTHTT | |
| SCHEMBL8167107 | 0.78 | CES2 (0.45) | SMN1; SMN2HPGDALDH1A1MAPTHTT | |
| SCHEMBL9498504 | 0.78 | CES2 (0.45) | SMN1; SMN2HPGDALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108947866-A | N-(2- methyl -3- Phenylbenzoyl)-N '-tertiary butyl hydrazine and its synthetic method | 安康学院 | 2018-12-07 | — | — | CN | disclosed |
| EP-0638545-B1 | Process for preparing 1,2-diacyl-2-t-alkylhydrazides | ROHM & HAAS (US) | 1999-10-13 | — | — | EP | disclosed |
| US-5767314-A | Selective acylation of monoalkylhydrazines | ROHM AND HAAS COMPANY (US) | 1998-06-16 | — | — | US | disclosed |
| US-5675037-A | REACTING UNSUBSTITUTED OR MONOALKYL-HYDRAZINES WITH TRICHLOROMETHYL ARYL KETONES | ROHM AND HAAS COMPANY (US) | 1997-10-07 | — | — | US | disclosed |
| US-5672723-A | SELECTIVE HYDROLYSIS OR ALCOHOLYSIS OF A MIXTURE OF 1-ACYL-1-ALKYLHYDRAZINE AND 1-ACYL-2-ALKYLHYDRAZINE USING AN ACID CATALYST TO OBTAIN AN ACID OR ESTER AND THE STABLE 1-ACYL-2-ALKYLHYRAZINE | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1997-09-30 | — | — | US | disclosed |
| EP-0639558-B1 | Process for preparation of 1-acyl-2-substituted-hydrazines | NIPPON KAYAKU KK (JP) | 1996-10-23 | — | — | EP | disclosed |
| EP-0492839-B1 | Selective acylation of hydrazines | ROHM & HAAS (US) | 1995-04-12 | — | — | EP | disclosed |
| EP-0639558-A1 | Process for preparation of 1-acyl-2-substituted-hydrazines | Nippon Kayaku Kabushiki Kaisha (JP) | 1995-02-22 | — | — | EP | disclosed |
| EP-0638545-A1 | Process for preparing 1,2-diacyl-2-t-alkylhydrazides | ROHM AND HAAS COMPANY (US) | 1995-02-15 | — | — | EP | disclosed |
| EP-0492839-A1 | Selective acylation of hydrazines | ROHM AND HAAS COMPANY (US) | 1992-07-01 | — | — | EP | disclosed |